{"id":580,"date":"2017-09-25T14:25:00","date_gmt":"2017-09-25T06:25:00","guid":{"rendered":"https:\/\/opentrons.com.cn\/?post_type=case&p=580"},"modified":"2023-12-26T14:41:50","modified_gmt":"2023-12-26T06:41:50","slug":"opentrons-user-interview-talking-genomics-with-gencoves-kaja-wasik","status":"publish","type":"case","link":"https:\/\/opentrons.com.cn\/resources\/customer-stories\/opentrons-user-interview-talking-genomics-with-gencoves-kaja-wasik\/","title":{"rendered":"Opentrons \u5ba2\u6237\u8bbf\u8c08 | \u4e0eGencove\u7684Kaja Wasik\u8c08\u8bba\u57fa\u56e0\u7ec4\u5b66"},"content":{"rendered":"\n

Kaja Wasik \u7684\u4f7f\u547d\u662f\u8ba9\u4f60\u60f3\u4e86\u89e3\u81ea\u5df1\u7684\u57fa\u56e0\u7ec4DNA\u5e8f\u5217\u3002\u201c\u57fa\u56e0\u7ec4\u6570\u636e\u968f\u7740\u4e16\u754c\u53d1\u5c55\u4e0e\u65f6\u4ff1\u8fdb\uff0c\u201dKaja\u89e3\u91ca\u8bf4\uff0c\u76ee\u524d\u79d1\u6280\u53d1\u5c55\u5df2\u7ecf\u5c06\u4ea7\u524d\u62a4\u7406\u548c\u75be\u75c5\u8bca\u65ad\u4e2d\u7684\u57fa\u56e0\u68c0\u6d4b\u5e38\u6001\u5316\u3002\u7136\u800c\uff0c\u7a76\u7adf\u8c01\u53ef\u4ee5\u8bbf\u95ee\u57fa\u56e0\u7ec4\u6570\u636e\u4ee5\u53ca\u5982\u4f55\u4f7f\u7528\u5b83\u5462\uff1f<\/p>\n\n\n\n

\u7136\u800c\uff0c\u7a76\u7adf\u8c01\u53ef\u4ee5\u8bbf\u95ee\u57fa\u56e0\u7ec4\u6570\u636e\u4ee5\u53ca\u5982\u4f55\u4f7f\u7528\u5b83\uff0c\u5f15\u53d1\u4e86\u533b\u5b66<\/a>\u3001\u4f26\u7406<\/a>\u548c\u5546\u4e1a\u754c<\/a>\u4e4b\u95f4\u7684\u8fa9\u8bba\u3002DNA \u6570\u636e\u7684\u4f7f\u7528\u8005\u5f80\u5f80\u751a\u81f3\u6ca1\u6709\u80fd\u529b\u81ea\u5df1\u4f7f\u7528\u5b83\u3002Kaja \u6b63\u5728\u52aa\u529b\u6539\u53d8\u8fd9\u4e00\u73b0\u72b6\u3002\u5979\u8868\u793a\uff0c\u8ba9\u4eba\u4eec\u80fd\u591f\u4e86\u89e3\u81ea\u5df1\u7684DNA\u5e8f\u5217\u201c\u8d4b\u4e88\u4e86\u4eba\u4eec\u529b\u91cf\u201d\u3002<\/p>\n\n\n\n

Kaja\uff08\u8054\u5408\u521b\u59cb\u4eba\u3001\u9996\u5e2d\u6218\u7565\u5b98\uff09\u3001\u5979\u7684\u8054\u5408\u521b\u59cb\u4eba Tomaz Berisa\uff08\u8054\u5408\u521b\u59cb\u4eba\u3001\u9996\u5e2d\u6280\u672f\u5b98\uff09\u548c Joe Pickrell\uff08\u8054\u5408\u521b\u59cb\u4eba\u3001\u9996\u5e2d\u6267\u884c\u5b98\uff09\u5728\u4ed6\u4eec\u7684\u521d\u521b\u516c\u53f8 Gencove <\/a>\u5f00\u53d1\u4e86\u4e00\u79cd\u65b0\u7684\u6d4b\u5e8f\u5e73\u53f0\u3002Gencove \u4ece\u53c2\u4e0e\u8005\u7684\u553e\u6db2\u4e2d\u5236\u5907\u57fa\u56e0\u7ec4\u5185\u5bb9\u4ee5\u8fdb\u884c\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u3002<\/p>\n\n\n\n

\u4ed6\u4eec\u4ece\u4e09\u4e2a\u65b9\u9762\u5bf9\u5176\u4ed6\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u670d\u52a1\u8fdb\u884c\u4e86\u6539\u8fdb\uff1a<\/p>\n\n\n\n

1 \u2013 \u4f7f\u7528\u4f4e\u8986\u76d6\u5ea6\u7684\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\uff0c\u800c\u4e0d\u662f SNP \u82af\u7247\uff08\u4e0b\u6587\u5c06\u8fdb\u4e00\u6b65\u4ecb\u7ecd\uff09\u3002<\/p>\n\n\n\n

2 \u2013 \u63d0\u4f9b\u6709\u5173\u53c2\u4e0e\u8005\u53e3\u8154\u5fae\u751f\u7269\u7fa4\u7684\u4fe1\u606f\u3002<\/p>\n\n\n\n

3 \u2013 \u63d0\u4f9b\u6240\u6709\u57fa\u56e0\u7ec4\u6570\u636e\u7684\u5f00\u653e API \u8bbf\u95ee\u7aef\u53e3\u3002<\/p>\n\n\n\n

\u53c2\u4e0e\u8005\u53ea\u9700\u652f\u4ed860\u7f8e\u5143\uff0c\u5373\u53ef\u83b7\u5f97\u8fd9\u4e9b\u4ee5\u53ca\u4e00\u5957\u6807\u51c6\u7684\u7956\u5148\u548c\u5065\u5eb7\u76f8\u5173\u6570\u636e\uff08\u76f8\u6bd4\u4e4b\u4e0b\uff0cAncestry.com \u621623 andMe \u7684\u4ef7\u683c\u4e3a 79 \u7f8e\u5143\u6216 199 \u7f8e\u5143\uff0c\u8fd9\u4e24\u5bb6\u516c\u53f8\u4e5f\u63d0\u4f9b\u57fa\u4e8e DNA \u6d4b\u5e8f\u7684\u7956\u5148\u4fe1\u606f\uff09\u3002<\/p>\n\n\n\n

\u4f60\u7684\u57fa\u56e0\u7ec4\u6570\u636e\u90fd\u5728\u4e00\u4e2a\uff08\u5f00\u6e90\uff09\u5e73\u53f0\u4e0a<\/h3>\n\n\n\n

Gencove\u7684\u521b\u65b0\u4e4b\u4e00\u5728\u4e8e\u5176\u754c\u9762\u8bbe\u8ba1\u3002\u9664\u4e86\u64cd\u4f5c\u7b80\u5355\u6613\u61c2\u4e4b\u5916\uff0c\u8be5\u5e73\u53f0\u5141\u8bb8\u7528\u6237\u4e0a\u4f20\u5e76\u5206\u6790\u5404\u79cd\u683c\u5f0f\u7684\u57fa\u56e0\u7ec4\u6570\u636e\u3002\u8fd9\u4e3a\u7528\u6237\u63d0\u4f9b\u4e86\u65b9\u4fbf\uff0c\u4ed6\u4eec\u53ef\u4ee5\u5c06\u81ea\u5df1\u901a\u8fc7\u5176\u4ed6\u516c\u53f8\u83b7\u53d6\u7684\u6570\u636e\u4e0e Gencove \u7684\u6570\u636e\u8fdb\u884c\u6bd4\u5bf9\u3002\u66f4\u4e3a\u72ec\u7279\u7684\u662f\uff0c\u6301\u6709\u57fa\u56e0\u7ec4\u6570\u636e\u7684\u4eba\u65e0\u9700\u4f7f\u7528 Gencove \u7684\u6d4b\u5e8f\u670d\u52a1\uff0c\u901a\u8fc7\u5176API\u5373\u53ef\u4e0a\u4f20\u5e76\u5206\u6790\u6570\u636e\uff0c\u4ece\u800c\u83b7\u53d6\u66f4\u591a\u4fe1\u606f\u3002<\/p>\n\n\n\n

\u5bf9\u4e8e\u90a3\u4e9b\u70ed\u8877\u4e8e\u7814\u7a76\u57fa\u56e0\u578b\u6216 DNA \u5e8f\u5217\u4e0e\u7279\u5f81\u4e4b\u95f4\u72ec\u7279\u5173\u7cfb\u7684\u7814\u7a76\u4eba\u5458\u6765\u8bf4\uff0c\u514d\u8d39\u4e14\u5f00\u6e90\u7684 API<\/a> \u662f\u4e00\u4e2a\u4e0d\u5c0f\u7684\u798f\u5229\u3002\u4ee5\u5bfb\u627e\u4e0e\u73ab\u7470\u9999\u5473\u76f8\u5173\u7684\u57fa\u56e0\u4e3a\u4f8b\uff0c\u7814\u7a76\u4eba\u5458\u4e4b\u524d\u8981\u4e48\u9700\u8981\u4ece\u5934\u5f00\u59cb\u5efa\u7acb\u81ea\u5df1\u7684\u7814\u7a76\u9879\u76ee\uff0c\u8981\u4e48\u9700\u8981\u4e0e\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u516c\u53f8\u5408\u4f5c\uff0c\u82b1\u8d39\u65f6\u95f4\u548c\u8d44\u91d1\u8fdb\u884c\u6570\u636e\u6388\u6743\u3002\u800c\u73b0\u5728\uff0c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u5229\u7528\u53c2\u4e0e\u8005\u540c\u610f\u63d0\u4f9b\u7684\u57fa\u56e0\u7ec4\u6570\u636e\uff08Kaja \u5f3a\u8c03\uff0c\u6bcf\u4e2a\u7814\u7a76\u9879\u76ee\u90fd\u9700\u8981\u83b7\u5f97\u7528\u6237\u540c\u610f\uff0c\u624d\u80fd\u4f7f\u7528\u5176\u5df2\u53bb\u9664\u6807\u8bc6\u7684\u5e8f\u5217\uff09\uff0c\u6784\u5efa\u7279\u5b9a\u7b97\u6cd5\uff0c\u63d0\u51fa\u5404\u79cd\u7814\u7a76\u95ee\u9898\u3002\u8fd9\u4e9b\u95ee\u9898\u65e2\u53ef\u4ee5\u662f\u50cf\u6c14\u5473\u68c0\u6d4b\u8fd9\u6837\u7b80\u5355\u7684\u7814\u7a76\uff0c\u4e5f\u53ef\u4ee5\u662f\u5bfb\u627e\u7f55\u89c1\u9057\u4f20\u75be\u75c5\u7b49\u66f4\u6df1\u5165\u7684\u7814\u7a76\u3002<\/p>\n\n\n\n

\u5c06\u6570\u636e\u6c47\u603b\u4ee5\u89e3\u7b54\u95ee\u9898<\/h3>\n\n\n\n

\u5bf9\u4e8e\u9057\u4f20\u6027\u75be\u75c5\u7684\u7814\u7a76\uff0cKaja \u548c Gencove \u56e2\u961f\u6709\u4e00\u4e2a\u6838\u5fc3\u76ee\u6807\uff1a\u5bfb\u627e\u66f4\u597d\u7684\u7406\u89e3\u3002\u867d\u7136\u53ea\u6709\u5c11\u6570\u75be\u75c5\u4e0e\u9057\u4f20\u6709\u5173\uff0c\u4f46 Gencove \u7684\u5f3a\u5927\u4e4b\u5904\u5728\u4e8e\u5c06\u5404\u79cd\u57fa\u56e0\u7ec4\u6570\u636e\u6c47\u603b\u5230\u4e00\u4e2a\u5e73\u53f0\u4e0a\uff0c\u4e3a\u7814\u7a76\u4eba\u5458\u63d0\u4f9b\u4e86\u5927\u91cf\u53ef\u4f9b\u7814\u7a76\u7684\u5e8f\u5217\u3002Kaja \u8868\u793a\uff1a\u201c\u6211\u4eec\u8ba4\u4e3a\uff0c\u8fd9\u4e9b\u5927\u578b\u961f\u5217\u7814\u7a76\u5c06\u5e2e\u52a9\u6211\u4eec\u627e\u5230\u90a3\u4e9b\u975e\u5e38\u7f55\u89c1\u7684\u7a81\u53d8\uff0c\u4f8b\u5982\uff0c\u767e\u4e07\u5206\u4e4b\u4e00\u7684\u7f55\u89c1\u75c5\u4f8b\u3002\u201d \u201c\u6211\u4eec\u5e0c\u671b\u968f\u7740\u6570\u636e\u96c6\u7684\u4e0d\u65ad\u589e\u5927\uff0c\u6211\u4eec\u80fd\u591f\u627e\u5230\u8fd9\u4e9b\u75c5\u4f8b\u3002\u201d<\/p>\n\n\n\n

Gencove \u6240\u4f7f\u7528\u7684\u6280\u672f\u6709\u52a9\u4e8e\u5bfb\u627e\u8fd9\u4e9b\u7f55\u89c1\u7684\u57fa\u56e0\u7a81\u53d8\uff1a\u4ed6\u4eec\u4f7f\u7528\u4f4e\u8986\u76d6\u5ea6\u7684\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u3002\u8fd9\u79cd\u6280\u672f\u5f00\u653e\u4e86\u57fa\u56e0\u7ec4\u4e2d\u5c1a\u672a\u88ab\u5176\u4ed6\u57fa\u56e0\u7ec4\u516c\u53f8\u901a\u8fc7SNP\u9635\u5217\u7814\u7a76\u8fc7\u7684\u90e8\u5206\u3002\u4f4e\u8986\u76d6\u5ea6\u7684\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u610f\u5473\u7740 Gencove \u968f\u673a\u5bf9\u53c2\u4e0e\u8005\u57fa\u56e0\u7ec4\u7684 10-20% \u8fdb\u884c\u6d4b\u5e8f\uff0c\u5e76\u5229\u7528\u73b0\u6709\u6570\u636e\u5e93\u4e2d\u7684\u5e8f\u5217\u63a8\u65ad\u51fa\u5176\u4f59\u90e8\u5206\u3002\u901a\u8fc7\u9057\u4f20\u63a8\u65ad\uff08\u4f7f\u7528\u7b97\u6cd5\u627e\u5230\u4e0e\u6d4b\u5e8f\u533a\u57df\u6700\u53ef\u80fd\u76f8\u5173\u7684\u672a\u8bfb DNA \u5e8f\u5217\uff09\uff0c\u4ed6\u4eec\u63d0\u9ad8\u4e86\u4f4e\u8986\u76d6\u5ea6 WGS \u7684\u529f\u7387\u548c\u5206\u8fa8\u7387\uff0c\u5e76\u63d0\u9ad8\u4e86\u9884\u6d4b\u51c6\u786e\u6027\uff0c\u4ee5\u6781\u9ad8\u7684\u51c6\u786e\u6982\u7387\u63d0\u4f9b\u6709\u5173\u6574\u4e2a\u57fa\u56e0\u7ec4\u7684\u4fe1\u606f\u3002<\/p>\n\n\n\n

Gencove \u4e5f\u5728\u52aa\u529b\u589e\u52a0\u5176\u6570\u636e\u5e93\u4e2d\u7684\u57fa\u56e0\u7ec4\u4ee3\u8868\u6027\uff0c\u8fd9\u5c06\u8fdb\u4e00\u6b65\u4e30\u5bcc\u4ed6\u4eec\u7684\u6570\u636e\u3002\u201c\u8bb8\u591a\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\u90fd\u662f\u5728\u6b27\u6d32\u767d\u79cd\u4eba\u8eab\u4e0a\u8fdb\u884c\u7684\uff0c\u591a\u6837\u6027\u4e0d\u8db3\uff0c\u201dKaja \u8bf4\u3002Gencove \u7684\u4e00\u4e2a\u5408\u4f5c\u4f19\u4f34\u662f\u4e00\u5bb6\u5370\u5ea6\u6d4b\u5e8f\u516c\u53f8\uff1a\u201c\u5982\u4eca\uff0c\u6211\u4eec\u62e5\u6709\u5370\u5ea6\u4eba\u7fa4\u6700\u51c6\u786e\u7684\u53c2\u8003\u57fa\u56e0\u7ec4\uff0c\u201d\u5979\u8bf4\u3002\u589e\u52a0\u6570\u636e\u5e93\u7684\u591a\u6837\u6027\u53ef\u80fd\u6709\u52a9\u4e8e\u53d1\u73b0\u66f4\u591a\u5728\u975e\u6b27\u6d32\u9057\u4f20\u80cc\u666f\u4e0b\u66f4\u5e38\u89c1\u7684\u9057\u4f20\u6027\u75be\u75c5\u3002<\/p>\n\n\n\n

Kaja \u6b22\u8fce\u4e0e\u90a3\u4e9b\u5e0c\u671b\u6536\u96c6\u5927\u91cf\u4eba\u7fa4\u5e76\u4ece\u5934\u5f00\u59cb\u6d4b\u5e8f\u7684\u4eba\u5efa\u7acb\u5408\u4f5c\u5173\u7cfb\uff0c\u65e0\u8bba\u4ed6\u4eec\u662f\u4e2a\u4eba\u3001\u5b66\u8005\u3001\u521d\u521b\u516c\u53f8\u8fd8\u662f\u5236\u836f\u516c\u53f8\u3002\u8fd9\u4e9b\u9879\u76ee\u4e0d\u4ec5\u53ef\u4ee5\u56de\u7b54\u5177\u4f53\u7684\u7814\u7a76\u95ee\u9898\uff0c\u8fd8\u53ef\u4ee5\u589e\u52a0\u8d8a\u6765\u8d8a\u591a\u7684\u6570\u636e\uff0c\u4e3a\u90a3\u4e9b\u53ef\u80fd\u6d89\u53ca\u65b0\u7b97\u6cd5\u5bfb\u627e\u5173\u8054\u7684\u9879\u76ee\u63d0\u4f9b\u8d44\u6e90\u3002<\/p>\n\n\n\n

OPENTRONS \u548c GENCOVE<\/h3>\n\n\n\n

Gencove \u7684\u81ea\u52a8\u5316\u6d41\u7a0b\u59cb\u4e8e OT-1 S\u3002OT-1 S \u4ece\u553e\u6db2\u8bd5\u7ba1\u4e2d\u5438\u53d6\u553e\u6db2\u6837\u672c\uff0c\u7136\u540e\u5c06\u5176\u8f6c\u79fb\u5230 96 \u5b54\u677f\u4e2d\uff0c\u4ee5\u4fbf\u8fdb\u884c\u8fdb\u4e00\u6b65\u5904\u7406\u3002\u8be5\u6d41\u7a0b\u8fd8\u4f7f\u7528\u4e86 Formulatrix Mantis \u8fdb\u884c\u677f\u586b\u5145\u548c Agilent Bravo \u8fdb\u884c\u5e76\u884c NGS \u6587\u5e93\u5236\u5907\u3002<\/p>\n\n\n\n

\u5bf9\u4e8e Kaja \u6765\u8bf4\uff0cOpentrons OT-1 \u7684\u5438\u5f15\u529b\u5728\u4e8e\u5176\u7ecf\u6d4e\u6027\u3002\u201c\u5b9e\u9a8c\u5ba4\u81ea\u52a8\u5316\u7684\u6210\u672c\u4ee4\u4eba\u9707\u60ca\uff0c\u201d\u5979\u8bf4\u3002\u201c\u4e00\u53f0\u80fd\u5b8c\u6210 OT-1 \u6240\u505a\u5de5\u4f5c\u7684\u673a\u5668\u4eba\uff0c\u6211\u88ab\u544a\u77e5\u9700\u8981\u82b1\u8d39 20 \u4e07\u81f3 35 \u4e07\u7f8e\u5143\u3002\u4f5c\u4e3a\u53ea\u6709\u4e09\u540d\u5458\u5de5\u7684\u521d\u521b\u516c\u53f8\uff0c\u6211\u65e0\u6cd5\u6295\u8d44\u5982\u6b64\u6602\u8d35\u7684\u4e1c\u897f\u3002Opentrons \u4e3a\u6211\u4eec\u63d0\u4f9b\u4e86\u51c6\u786e\u548c\u53ef\u9884\u6d4b\u7684\u7ed3\u679c\uff0c\u800c\u4e14\u4ef7\u683c\u975e\u5e38\u5b9e\u60e0\u3002\u201d<\/p>\n\n\n\n

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