{"id":2817,"date":"2024-05-30T22:11:27","date_gmt":"2024-05-30T14:11:27","guid":{"rendered":"https:\/\/opentrons.com.cn\/?post_type=knowledge2&p=2817"},"modified":"2024-09-03T17:05:47","modified_gmt":"2024-09-03T09:05:47","slug":"smkxdldxxqs","status":"publish","type":"knowledge2","link":"https:\/\/opentrons.com.cn\/knowledge2\/smkxdldxxqs\/","title":{"rendered":"\u751f\u547d\u79d1\u5b66\u7684 6 \u5927\u65b0\u5174\u8d8b\u52bf"},"content":{"rendered":"\n

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    \n
  1. \u81ea\u52a8\u5316\u77e5\u8bc6
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    Ginkgo Bioworks \u4e3a\u5ba2\u6237\u8bbe\u8ba1\u5b9a\u5236\u751f\u7269\u4f53\uff0c\u5e76\u5efa\u7acb\u81ea\u5df1\u7684\u5de5\u5382\uff0c\u5229\u7528\u8f6f\u4ef6\u548c\u786c\u4ef6\u81ea\u52a8\u5316\u6765\u6269\u5c55\u8be5\u6d41\u7a0b\u3002Synthego \u662f\u7b2c\u4e00\u5bb6\u4e5f\u662f\u552f\u4e00\u4e00\u5bb6\u63d0\u4f9b\u5168\u6808\u57fa\u56e0\u7ec4\u5de5\u7a0b\u89e3\u51b3\u65b9\u6848\u7684\u516c\u53f8\uff0c\u901a\u8fc7\u5229\u7528\u57fa\u4e8e\u4e91\u7684\u8f6f\u4ef6\u81ea\u52a8\u5316\u6765\u5b9e\u73b0\u8fd9\u4e00\u76ee\u6807\u3002Synthace \u540c\u65f6\u5229\u7528\u786c\u4ef6\u548c\u8f6f\u4ef6\u6765\u5e2e\u52a9\u5927\u578b\u81ea\u52a8\u5316\u5b9e\u9a8c\u5ba4\u3002\u5f53\u7136\uff0c\u4e16\u754c\u5404\u5730\u6709\u6570\u767e\u540d\u751f\u7269\u5b66\u5bb6\u4f7f\u7528 Opentrons \u8f6f\u4ef6\u548c\u786c\u4ef6\u6765\u81ea\u52a8\u5316\u5404\u79cd\u5b9e\u9a8c\u7684\u534f\u8bae\u548c\u5de5\u4f5c\u6d41\u7a0b\uff0c\u4ece\u57fa\u672c\u7a00\u91ca\u5230 PCR \u5236\u5907\u548c NGS\u3002\u63a2\u7d22\u8fd9\u4e9b\u516c\u53f8\u5982\u4f55\u4f7f\u7528\u81ea\u52a8\u5316\u5c06\u6709\u52a9\u4e8e\u60a8\u4e86\u89e3\u81ea\u52a8\u5316\u5982\u4f55\u6539\u53d8\u751f\u547d\u79d1\u5b66\u7814\u7a76\u3002<\/p>\n\n\n\n

      \n
    1. \u5f00\u6e90\u3001\u534f\u4f5c\u548c\u53ef\u5171\u4eab\u6027\u6280\u80fd<\/li>\n<\/ol>\n\n\n\n

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      \u968f\u7740\u751f\u547d\u79d1\u5b66\u5b66\u79d1\u4e2d\u5f00\u6e90\u7684\u4f7f\u7528\u4e0d\u65ad\u53d1\u5c55\uff0c\u7f16\u7801\u548c\u6570\u636e\u5171\u4eab\u65b9\u6cd5\u65b9\u9762\u7684\u5b9e\u8df5\u4e13\u4e1a\u77e5\u8bc6\u5c06\u6210\u4e3a\u751f\u547d\u79d1\u5b66\u5bb6\u7684\u4e3b\u8981\u8d44\u4ea7\u2014\u2014\u56e0\u6b64\uff0c\u73b0\u5728\u719f\u6089\u5176\u4e2d\u4e00\u4e9b\u5de5\u5177\u5c06\u4e3a\u60a8\u5728\u672a\u6765\u63d0\u4f9b\u4f18\u52bf\u3002\u5f00\u6e90\u534f\u8bae\u5171\u4eab\u5e73\u53f0\u662f\u4e00\u4e2a\u5f88\u597d\u7684\u8d77\u70b9\uff0c\u4f8b\u5982 Protocols.io \u548c Opentrons \u534f\u8bae\u5e93\uff0c\u5b83\u4eec\u5141\u8bb8\u79d1\u5b66\u5bb6\u53d1\u73b0\u548c\u5171\u540c\u5f00\u53d1\u534f\u8bae\uff0c\u4ee5\u53ca Plasmotron.org\uff0c\u5b83\u5141\u8bb8\u7528\u6237\u5728\u5f00\u6e90\u4ee3\u7801\u7684\u57fa\u7840\u4e0a\u8fdb\u884c\u6784\u5efa\u3002<\/p>\n\n\n\n

      \"\u751f\u547d\u79d1\u5b66\u7684<\/figure>\n\n\n\n
        \n
      1. \u79d1\u5b66\u4f20\u64ad
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          \n
        1. \u673a\u5668\u5b66\u4e60\u548c\u4eba\u5de5\u667a\u80fd
          \u867d\u7136\u542c\u8d77\u6765\u5f88\u6709\u672a\u6765\u611f\uff0c\u4f46\u6211\u4eec\u6bcf\u5929\u90fd\u88ab\u673a\u5668\u5b66\u4e60\u8f85\u52a9\u7684\u4eba\u5de5\u667a\u80fd\u5e94\u7528\u6240\u5305\u56f4\uff1a\u667a\u80fd\u624b\u673a\u4e0a\u7684\u8bed\u97f3\u52a9\u624b\u3001\u7f51\u7ad9\u4e0a\u7684\u5b9e\u65f6\u804a\u5929\u529f\u80fd\u3001\u793e\u4ea4\u5a92\u4f53\u63a8\u9001\u4e2d\u7684\u5b9a\u5411\u5e7f\u544a\u7b49\u7b49\u3002\u8fd9\u4e9b\u5e94\u7528\u5229\u7528\u590d\u6742\u7684\u7b97\u6cd5\u548c\u6d77\u91cf\u6570\u636e\u96c6\u6765\u8bad\u7ec3\u8ba1\u7b97\u673a\u50cf\u4eba\u7c7b\u4e00\u6837\u5de5\u4f5c\u548c\u53cd\u5e94\u3002\u8fd9\u4e2a\u8fc7\u7a0b\u6539\u8fdb\u4e86\u8ba1\u7b97\u673a\u7684\u5b66\u4e60\u8fc7\u7a0b\uff0c\u4f7f\u5b83\u4eec\u5728\u54cd\u5e94\u6761\u4ef6\u548c\u4ea7\u751f\u7ed3\u679c\u65b9\u9762\u66f4\u52a0\u9ad8\u6548\u2014\u2014\u8fc5\u901f\u63d0\u9ad8\u4e86\u672a\u6765\u53d1\u73b0\u7684\u901f\u5ea6\u3002<\/li>\n<\/ol>\n\n\n\n

          \u5728\u751f\u547d\u79d1\u5b66\u9886\u57df\uff0c\u673a\u5668\u5b66\u4e60\u5df2\u7ecf\u901a\u8fc7\u5176\u533a\u5206\u7ec6\u80de\u3001\u5206\u6790\u57fa\u56e0\u7ec4\u6570\u636e\u3001\u8fdb\u884c\u56fe\u50cf\u5206\u6790\u548c\u6bd4\u4ee5\u524d\u7684\u65b9\u6cd5\u66f4\u65e9\u3001\u66f4\u7075\u654f\u5730\u68c0\u6d4b\u75be\u75c5\u6307\u6807\u7684\u80fd\u529b\uff0c\u5f7b\u5e95\u6539\u53d8\u4e86\u7814\u7a76\u548c\u8bca\u65ad\u7684\u901f\u5ea6\u3002\u4e00\u4e2a\u4e3b\u8981\u7684\u589e\u957f\u9886\u57df\u662f\u5229\u7528\u673a\u5668\u5b66\u4e60\u6765\u8bbe\u8ba1\u5b9e\u9a8c\u3002Asimov \u4f7f\u7528\u5f00\u6e90\u6570\u636e\u5f00\u53d1\u673a\u5668\u5b66\u4e60\u7b97\u6cd5\uff0c\u5c06\u5927\u89c4\u6a21\u6570\u636e\u96c6\u4e0e\u751f\u7269\u5b66\u673a\u68b0\u6a21\u578b\u8054\u7cfb\u8d77\u6765\uff0c\u4ee5\u6784\u5efa\u751f\u7269\u7535\u8def\u5b9e\u9a8c\u3002Cello \u5229\u7528\u673a\u5668\u5b66\u4e60\u6765\u81ea\u52a8\u8bbe\u8ba1\u6d3b\u7ec6\u80de\u4e2d\u7684\u751f\u7269\u7535\u8def\u3002\u53e6\u4e00\u4e2a\u4e3b\u8981\u7684\u589e\u957f\u9886\u57df\u662f\u751f\u7269\u4fe1\u606f\u5b66\u3002 Deep Genomics \u5229\u7528\u673a\u5668\u5b66\u4e60\u6765\u6536\u96c6\u3001\u5206\u6790\u548c\u5904\u7406\u57fa\u56e0\u7ec4\u6570\u636e\uff0c\u4ee5\u5f00\u53d1\u66f4\u597d\u3001\u66f4\u6709\u9488\u5bf9\u6027\u7684\u836f\u7269\u3002\u4e00\u4e9b\u516c\u53f8\uff0c\u5982 Atomwise\uff0c\u751a\u81f3\u4f7f\u7528\u6df1\u5ea6\u5b66\u4e60\u6846\u67b6\u5c1d\u8bd5\u5728\u8f6f\u4ef6\u4e2d\u7b5b\u9009\u5019\u9009\u836f\u7269\u3002\u719f\u6089\u8fd9\u4e9b\u65b0\u5174\u5e94\u7528\u5c06\u6709\u52a9\u4e8e\u60a8\u638c\u63e1\u8be5\u6280\u672f\u7684\u672a\u6765\u7528\u9014\u3002<\/p>\n\n\n\n

            \n
          1. \u4f7f\u7528 CRISPR \u8fdb\u884c\u57fa\u56e0\u7f16\u8f91
            2000 \u5e74\u4ee3\u4e2d\u671f\u53d1\u73b0\u7684 CRISPR \u662f\u751f\u547d\u79d1\u5b66\u7684\u4e00\u4e2a\u8f6c\u6298\u70b9\uff0c\u56e0\u4e3a\u5b83\u53ef\u7528\u4e8e\u57fa\u56e0\u5de5\u7a0b\u3002\u867d\u7136\u6211\u4eec\u73b0\u5728\u90fd\u719f\u6089 CRISPR \u5e73\u53f0\uff0c\u4f46\u57fa\u56e0\u7f16\u8f91\u5e73\u53f0\u7684\u5e94\u7528\u5f71\u54cd\u6df1\u8fdc\u2014\u2014\u5e76\u4e14\u7ecf\u5e38\u4e0e\u8bb8\u591a\u5176\u4ed6\u65b0\u5174\u9886\u57df\u91cd\u53e0\u3002Oxford Genetics \u63d0\u4f9b\u7528\u4e8e\u57fa\u56e0\u7f16\u8f91\u7684\u5b9e\u9a8c\u8bbe\u8ba1\u5de5\u5177\uff0c\u5e2e\u52a9\u7b80\u5316\u5de5\u4f5c\u6d41\u7a0b\u3002Synthego \u518d\u6b21\u5229\u7528\u673a\u5668\u5b66\u4e60\u6765\u63a8\u52a8\u57fa\u56e0\u5de5\u7a0b\u4e2d\u7684\u5b9e\u9a8c\u8bbe\u8ba1\u3002 CRISPR Therapeutics \u5229\u7528 CRISPR \u57fa\u56e0\u7f16\u8f91\u5e73\u53f0\u5f00\u53d1\u9488\u5bf9\u8840\u6db2\u75be\u75c5\uff08\u5982\u9570\u72b6\u7ec6\u80de\u6027\u8d2b\u8840\uff09\u7684\u836f\u7269\uff0c\u800c Caribou Biosciences\u3001Editas Medicine \u548c Cellectis \u5219\u5229\u7528 CRISPR \u548c\u5176\u4ed6\u57fa\u56e0\u7f16\u8f91\u6280\u672f\uff08\u5982 TALEN\uff09\u6765\u4fee\u6539 T \u7ec6\u80de\u4ee5\u9488\u5bf9\u764c\u7ec6\u80de\u3002<\/li>\n<\/ol>\n\n\n\n

            \u9884\u8ba1\u5230 2023 \u5e74\uff0c\u5168\u7403 CRISPR \u5e02\u573a\u5c06\u589e\u957f 6 \u500d\uff0c\u8fbe\u5230 30 \u4ebf\u7f8e\u5143\uff0c\u56e0\u6b64\u672a\u6765\u751f\u547d\u79d1\u5b66\u5b9e\u9a8c\u5ba4\u4e2d\u5229\u7528\u57fa\u56e0\u7f16\u8f91\u5de5\u5177\u7684\u673a\u4f1a\u5e94\u8be5\u4e0d\u80dc\u679a\u4e3e\u3002<\/p>\n\n\n\n

              \n
            1. \u5355\u7ec6\u80de\u6280\u672f
              \u5feb\u901f\u53d1\u5c55\u7684\u6280\u672f\u5141\u8bb8\u5c06\u86cb\u767d\u8d28\u7ec4\u5b66\u3001\u57fa\u56e0\u7ec4\u5b66\u3001\u8f6c\u5f55\u7ec4\u5b66\u548c\u8868\u89c2\u9057\u4f20\u5b66\u6280\u672f\u5e94\u7528\u4e8e\u5355\u7ec6\u80de\uff0c\u4e3a\u63a7\u5236\u53d1\u80b2\u3001\u57fa\u56e0\u8868\u8fbe\u3001\u7ec4\u7ec7\u5f02\u8d28\u6027\u548c\u75be\u75c5\u673a\u5236\u7684\u590d\u6742\u751f\u7269\u8fc7\u7a0b\u63d0\u4f9b\u4e86\u65b0\u9896\u800c\u5173\u952e\u7684\u89c1\u89e3\u3002\u8fd9\u4e9b\u6280\u672f\u5bf9\u4e8e\u5206\u6790\u5faa\u73af\u80bf\u7624\u7ec6\u80de\u548c\u7a00\u6709\u5e72\u7ec6\u80de\u7b49\u751f\u7269\u73b0\u8c61\u7279\u522b\u6709\u7528\uff0c\u800c\u8fd9\u4e9b\u73b0\u8c61\u5bf9\u4e8e\u6807\u51c6\u201c\u7ec4\u5b66\u201d\u5e94\u7528\u6765\u8bf4\u5177\u6709\u6311\u6218\u6027\uff0c\u751a\u81f3\u662f\u4e0d\u53ef\u80fd\u7684\u3002\u57fa\u56e0\u7ec4\u7f16\u8f91\u3001\u81ea\u52a8\u5316\u548c\u5fae\u6d41\u63a7\u6280\u672f\u7684\u540c\u6b65\u53d1\u5c55\u8fdb\u4e00\u6b65\u4fc3\u8fdb\u4e86\u5355\u7ec6\u80de\u5e94\u7528\u4e2d\u5e38\u89c1\u7684\u8f83\u5c0f\u6837\u672c\u7684\u5feb\u901f\u9ad8\u901a\u91cf\u5206\u6790\u300210x Genomics \u4f7f\u7528\u5355\u7ec6\u80de\u764c\u75c7\u57fa\u56e0\u7ec4\u5b66\u68c0\u6d4b\u6765\u5206\u6790\u764c\u7ec6\u80de\u3002Metafluidics \u662f\u4e00\u4e2a\u7528\u4e8e\u590d\u5236\u6216\u91cd\u65b0\u6df7\u5408\u5fae\u6d41\u63a7\u8bbe\u5907\u7684\u5f00\u6e90\u8bbe\u8ba1\u548c\u534f\u8bae\u6587\u4ef6\u6570\u636e\u5e93\uff0c\u662f\u8be5\u9886\u57df\u7684\u4e00\u4e2a\u5f88\u597d\u7684\u4fe1\u606f\u5b58\u50a8\u5e93\u3002<\/li>\n<\/ol>\n\n\n\n

              \u5355\u7ec6\u80de\u5206\u6790\u9886\u57df\u7684\u589e\u957f\u53d7\u5230\u57fa\u7840\u7814\u7a76\u4ee5\u53ca\u5bf9\u65e9\u671f\u75be\u75c5\u68c0\u6d4b\u6280\u672f\u3001\u4ea7\u524d\u7b5b\u67e5\u3001\u751f\u7269\u6807\u5fd7\u7269\u53d1\u73b0\u3001\u6db2\u4f53\u6d3b\u68c0\u548c\u751f\u7269\u836f\u7269\u5f00\u53d1\u65e5\u76ca\u589e\u957f\u7684\u9700\u6c42\u7684\u63a8\u52a8\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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